报告称,要意识到药物是如何影响心律的

美国心脏协会沙巴足球体育平台报道

Elena Brovko/iStock,盖蒂图片社
(Elena Brovko/iStock,盖蒂图片社)

Many commonly used medications can cause or worsen irregular heartbeats known as arrhythmias, and health care professionals need to pay attention to the risks, 根据一份新的报告.

美国心脏协会 科学声明, 周二发表在《沙巴体育平台点击进入》杂志上, examined the effects of over-the-counter and prescription medicines, 包括一些已被研究用于对抗COVID-19的药物.

"Much remains unknown about the underlying mechanisms of arrhythmias associated with specific medications, and further research is needed to better understand risk factors and treatment options,——詹姆斯·E. Tisdale, chair of the statement's writing committee, said in a news release.

"We hope raising awareness will result in clinicians being attentive to risk factors, 和避免, 在可能的情况下, medications that can cause or worsen arrhythmias in patients who are at higher risk,蒂斯代尔说。, who is professor of pharmacy practice at the College of Pharmacy at Purdue University and an adjunct professor at Indiana University School of Medicine.

心律失常可以由基因引起, 心脏病, 高血压, 电解质失衡或其他因素. During an arrhythmia, a heart can beat too fast, too slowly or with an irregular rhythm.

有心脏病病史的人, 心脏病 or previous heart surgery are more likely to develop an irregular heartbeat after exposure to certain medications. Other risk factors for medication-induced arrhythmias include older age, deficiencies of potassium or magnesium and excessive alcohol use.

"Many commonly used medications can cause irregular heartbeats as a side effect,蒂斯代尔说。. “虽然风险相对较低, it is important for health care professionals to consider that their patient's arrhythmia could be caused or worsened by a medication."

药物可引起几种类型的心律失常. Often there are no symptoms, but some people feel their heart racing or fluttering. 他们可能会头晕、晕厥或呼吸困难.

如果心律失常不及时治疗, 心脏可能无法向身体输送足够的血液, 哪些会损害心脏, 大脑或其他器官. Some arrhythmias are life-threatening and require immediate treatment.

Among the medications that can disturb heart rhythms are chloroquine, 羟氯喹和阿奇霉素, 哪些已用于管理COVID-19, 写作小组注意到. 在六月和七月 Food and Drug Administration revoked emergency use and issued a warning against the use of hydroxychloroquine or chloroquine for the treatment of COVID-19 outside of a clinical trial or hospital.

建议用于治疗COVID-19的其他药物, 比如洛匹那韦/利托那韦, also have the potential to interfere with the heart's normal rhythm, 报告说.

Tisdale warned that patients should not alter their drug regimens on their own. "Medications are extremely important and beneficial for treating a large variety of diseases and chronic health conditions, and patients should not change or stop taking any of their medicines without talking with their health care professional."

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美国心脏协会沙巴足球体育平台报道

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